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用抗二二三５０６倍以上的淡色库蚊品系，对有机氯、有机磷、氨基甲酸酯及拟除虫菊酯类杀虫剂共１４种药物进行交叉抗性的生物测定。结果表明，与六六六、敌百虫、杀螟硫磷、仲丁威。残杀成均未发现明显的交互抗性：而与９种拟除虫菊酯类药物则均产生不同程度的交互抗性，其中速灭灵较原Ｐ代品系高１３０．０４倍，杀灭菊酯增加７９．５９倍，二氯苯醚菊酯增加６６．６倍。提示以往曾用二二三作为主要杀虫药剂并已产生抗性的地区，今后在选用以拟除虫菊酯类作为当地替代药剂时，应有选择地注意用药品种及数量。同时分析了不同种类杀虫剂产生交互抗性的不同原因及有关机理。
A cross-resistance bioassay was carried out on fourteen drugs of organochlorine, organophosphorus, carbamate and pyrethroid insecticides against Culex pipiens pallens which was more than 506 times higher than that of Erzan. The results showed that, with BHC, trichlorfon, fenitrothion, sec-butyl Ding Wei. No significant cross-resistance was found in all the three species of pyrethroid insecticides: 9-pyrethroid-resistant drugs were cross-resistant to each other, of which deoxyschryptamycin was 130.04-fold higher than that of the original P-generation strain, 79.59-fold, permethrin increased by 66.6-fold. In the past, it was suggested that in areas where 224 has been used as the main insecticide and resistance has been developed, the choice of pyrethroids as an alternative medicine should be given selective attention in the future. At the same time, the different causes and mechanisms of cross-resistance of different insecticides were analyzed.