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新型隐球菌脑膜炎是常见的中枢神经系统真菌病,其发病率虽较结核性脑膜炎低,但随着抗生素和肾上腺皮质类固醇的广泛应用,它的发病率亦随之逐年升高,应引起临床上足够重视。本文对近年来有关新型隐球菌脑膜炎在诊断和治疗方面的一些进展作一综述。病原和入侵途径新型隐球菌呈球形或卵圆形,直径5～20μm,有出芽的孢子,但无菌丝,菌体周围有较厚的荚膜,对温度及酸碱度的变化较为敏感,不耐高温。
Cryptococcus neoformans meningitis is a common central nervous system fungal disease, its incidence is lower than tuberculous meningitis, but with the widespread use of antibiotics and adrenal corticosteroids, its incidence has also increased year by year, should cause Clinic enough attention. This article reviews recent advances in the diagnosis and treatment of Cryptococcus neoformans meningitis. Pathogen and invasion of Cryptococcus neoformans spherical or oval, diameter 5 ~ 20μm, sprouting spores, but no mycelium, thicker capsule around the cell body, the temperature and pH changes are more sensitive, intolerant high temperature.