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本实验是为了探索宣威肺癌病因和肺癌早期危险性评价方法做一点尝试，应用３２Ｐ后标记法检测了宣威３０例（实验组）、昆明１０例（对照组）肺癌病人的纤维支气管镜（纤支镜）刷落细胞的多环芳烃（ＰＡＨ）－ＤＮＡ加合物。结果表明宣威肺癌病人的ＰＡＨ－ＤＮＡ加合物水平远远高于对照组。该结果从分子水平上证明宣威室内煤烟污染与肺癌有直接联系，ＤＮＡ加合物的检测可以作为人群危险性评价的指标。
This experiment is to try to explore the causes of lung cancer in Xuanwei and early risk assessment methods for lung cancer. The 32P posterior labeling method was used to detect the fiberoptic bronchoscopes in 30 cases of Xuanwei (experimental group) and 10 cases of Kunming lung cancer (control group). Bronchoscope) brush off the cell’s polycyclic aromatic hydrocarbon (PAH)-DNA adducts. The results showed that the PAH-DNA adduct levels in Xuanwei lung cancer patients were much higher than those in the control group. This result proves that there is a direct link between the pollution of soot in Xuanwei indoor and lung cancer from the molecular level. The detection of DNA adducts can be used as an indicator of population risk assessment.