一般流行病学材料由于白喉类毒素的广泛应用,七十年代以来,白喉在欧美国家除个别地区有小规模的暴发流行外,已不构成重大威胁。一些国家即使在发病率较高的年份,其发病地区亦有明显的局限性。例如美国1969～1970年发病率为0.21/10万,全国只有3％的郡有病例发生。病人症状一般都较轻,病死率亦趋下降,这种现象在东、西欧都有报告。检出的白喉杆菌生物型 General Epidemiological Materials Due to the widespread use of diphtheria toxoid, diphtheria has not posed a significant threat to Europe and the United States except for a small outbreak in some areas since the 1970s. In some countries with high incidence, there are obvious limitations in their areas of incidence. For example, the incidence of the United States from 1969 to 1970 was 0.21 / 100,000, with only 3% of the county-wide cases occurring in the country. Patient symptoms are generally mild, mortality also tends to decline, this phenomenon has been reported in East and West Europe. Detection of diphtheria bacillus biotype