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目的探讨缩宫素、654-2、安定联合应用的疗效及对产程的影响。方法采用缩宫素、654-2及安定联合应用180例,同时取缩宫素加安定组100例,单用缩宫素对照组100例,三组资料进行分析、比较。结果联合用药组加速宫颈口扩张,缩短产程效果显著(P<0.01),降低剖宫产率(P<0.05),且对胎儿宫内窘迫、羊水污染、新生儿窒息及产后出血率无明显差异(P>0.05)。结论缩宫素静滴、654-2加安定联合应用于足月妊娠引产,不失为一种有效的引产方法,对促进产程进展效果肯定。
Objective To investigate the curative effect of oxytocin and 654-2 combined with diazepam and its effect on labor process. Methods Using oxytocin, 654-2 and diazepam combined 180 cases, taking oxytocin and diazepam 100 cases, oxytocin alone control group 100 cases, three groups of data were analyzed and compared. Results The combined treatment group accelerated cervical dilatation and shortened labor process significantly (P <0.01), reduced cesarean section rate (P <0.05), and had no significant difference in fetal distress, amniotic fluid contamination, neonatal asphyxia and postpartum hemorrhage rate (P> 0.05). Conclusion oxytocin intravenous injection of 654-2 plus diazepam combined with full-term pregnancy induction of labor, after all, an effective method of induction of labor, to promote the progress of labor affirmation.