论文部分内容阅读
目的:了解脑出血后缺血性脑损害的发病机制,探讨尼莫地平对脑出血后缺血性脑损害的临床疗效。方法:选择我院2011年6月-2013年4月收治的90例脑出血后缺血性脑损害患者作为观察对象,将其随机分为观察组和对照组。对照组40例,使用常规治疗手段,观察组50例,在对照组的基础上使用尼莫地平进行治疗,观察两组患者的原发病灶缺血体积、血肿周围的局部脑血流量和远隔部位的局部脑血流量变化以及神经功能损伤情况,并进行比较。结果:两组治疗前后原发病灶缺血体积、血肿周围的局部脑血流量和远隔部位的局部脑血流量变化比较,具有显著统计差异(P<0.01);两组治疗前后神经功能损伤情况比较,具有显著统计差异(P<0.05)。结论:尼莫地平可改善脑出血后缺血性脑损害患者的局部脑缺血状况,有效减轻缺血性脑损害,对提高患者的生活质量有积极意义,值得临床推广。
Objective: To investigate the pathogenesis of ischemic brain damage after cerebral hemorrhage and to explore the clinical effect of nimodipine on ischemic brain damage after intracerebral hemorrhage. Methods: Ninety patients with ischemic brain damage after cerebral hemorrhage admitted in our hospital from June 2011 to April 2013 were selected as the observation object, which were randomly divided into observation group and control group. Control group of 40 cases, the use of conventional treatment, the observation group of 50 patients on the basis of the control group treated with nimodipine, the two groups of patients with primary lesion volume, local blood flow around the hematoma and distant Regional cerebral blood flow changes and neurological damage, and compared. Results: Before and after treatment, the changes of ischemic volume of primary lesion, local cerebral blood flow around hematoma and local cerebral blood flow at distant sites were significantly different (P <0.01); The neurological impairment Compared with significant statistical difference (P <0.05). Conclusion: Nimodipine can improve ischemic brain damage in patients with cerebral ischemia after cerebral ischemia, effectively reduce ischemic brain damage, to improve the quality of life of patients with positive significance, worthy of clinical promotion.