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目的:探讨复方甲硝唑阴道栓在84例阴道炎中的疗效。方法:选取2013年1月到2014年4月我院收治的167例阴道炎患者作为研究对象,并随机分为对照组(n=83)与观察组(84例)。给予观察组复方甲硝唑阴道栓治疗,给予对照组甲硝唑与制霉素软膏治疗,对比两组治疗疗效以及不良反应率。结果:治疗后,观察组的总有效率为100.00%,明显高于对照组(86.75%)(X2=4.436,P=0.035)。观察组无不良反应发生,对照组出现了2例胃部不适,2例头晕,对照组不良反应率为4.82%,两组不良反应率对比无统计学差异(X2=0.790,P=0.374)。结论:复方甲硝唑阴道栓治疗阴道炎的疗效显著,有效改善阴道炎患者的临床症状,不良反应少见,适于在临床应用、推广。
Objective: To investigate the curative effect of compound metronidazole vaginal suppository in 84 cases of vaginitis. Methods: A total of 167 patients with vaginitis treated in our hospital from January 2013 to April 2014 were selected and randomly divided into control group (n = 83) and observation group (n = 84). The observation group was treated with compound metronidazole vaginal suppository, and the control group was treated with metronidazole and nystatin ointment. The curative effect and adverse reaction rate were compared between the two groups. Results: After treatment, the total effective rate in the observation group was 100.00%, significantly higher than that in the control group (86.75%) (X2 = 4.436, P = 0.035). There were no adverse reactions in the observation group. There were 2 cases of stomach discomfort in the control group and 2 cases of dizziness. The rate of adverse reactions in the control group was 4.82%. There was no significant difference between the two groups (χ2 = 0.790, P = 0.374). Conclusion: The compound metronidazole vaginal suppository has significant curative effect on vaginitis and effectively improves the clinical symptoms of vaginitis patients with rare adverse reactions. It is suitable for clinical application and promotion.