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Current therapies for gliomas often fail to address their infiltrative nature.Conventional treatments leave be-hind small clusters of neoplastic cells,resulting in eventual tumor recurrence.In the present study,we have e-valuated the antitumor activity of neural progenitor cells against gliomas when stereotactically injected into nucleusCaudatus of Fisher rats.We show that the rat neural progenitor cell lines HiB5 and ST14A,from embryonic hip-pocampus and striatum primordium,respectively,are able to prolong animal survival and,in 25%of the cases,
Current therapies for gliomas often fail to address their infiltrative nature. Conventional treatments leave be-hind small clusters of neoplastic cells, resulting in eventual tumor recurrence. In the present study, we have e-valuated the antitumor activity of neural progenitor cells against gliomas when stereotactically injected into nucleus Caudatus of Fisher rats. We show that the rat neural progenitor cell lines HiB5 and ST14A, from embryonic hip-pocampus and striatum primordium, respectively, are able to prolong animal survival and, in 25% of the cases,