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目的探讨念珠菌感染的病原学依据和危险因素。方法选取本院2012年收治的患者可疑感染部位进行培养,如血、痰、分泌物、黏膜组织、积液等,统计培养出阳性菌株,并分析念珠菌感染的危险因素。结果共培养240株阳性念珠菌感染菌株,其中140株白色念珠菌,占58.3%;光滑念珠菌52株,占21.7%;25例克柔念珠菌,占10.4%;15株热带念珠菌,占6.25%;8例近平滑念珠菌,占3.3%。念珠菌感染的危险因素主要有:患者过长的住院时间、多种广谱抗生素应用、年龄偏大、留置管路、介入治疗、血液透析、高营养疗法等方面。结论分析念珠菌感染的病原学依据及危险因素,对预防感染发生,选取合理有效的控制手段有着积极的促进作用。
Objective To investigate the etiological basis and risk factors of candida infection. Methods The suspicious cases were collected from our hospital in 2012, such as blood, sputum, secretions, mucosa and effusion. The positive strains were collected and the risk factors of Candida infection were analyzed. Results A total of 240 strains of positive Candida were inoculated, of which 140 strains were Candida albicans (58.3%), Candida glabrata (21.7%), 25 Candida krusei (10.4%), 15 Candida tropicalis 6.25%; 8 cases of Candida parapsilosis, accounting for 3.3%. Candida infection risk factors are: patients with long hospital stay, a variety of broad-spectrum antibiotics, older, indwelling pipeline, interventional therapy, hemodialysis, nutrition therapy and so on. Conclusions The etiological basis and risk factors of Candida infection are positive for promoting the prevention of infection and selecting reasonable and effective control measures.