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目的:探讨阿托伐他汀对阵发性房颤或持续性房颤复律后的预防作用及护理方法。方法:将100例阵发性房颤或持续性房颤复律后患者随机分为治疗组与对照组各50例,两组均给予抗血小板药物、抗心律失常药物等常规治疗,治疗组在常规治疗基础上加用阿托伐他汀10 mg/d,对照组口服安慰剂,服药1年,随访1.5年。结果:治疗组阵发性房颤发作次数减少>50%比例高于对照组(P<0.05),阵发性房颤转为持续性或永久性房颤比例、持续性房颤复律后再发率、发生左房扩大者比例、血栓栓塞发生率均低于对照组(P<0.05);随访期间急性房颤发作患者治疗组使用胺碘酮复律剂量及电复律能量、次数均低于对照组(P<0.05)。结论:阿托伐他汀能有效预防或减少房颤发作,治疗期间护理人员应给予患者健康教育和心理疏导,可改善预后、提高生活质量。
Objective: To investigate the preventive effect and nursing of atorvastatin on patients with paroxysmal atrial fibrillation or persistent atrial fibrillation. Methods: One hundred patients with paroxysmal atrial fibrillation or persistent atrial fibrillation were randomly divided into treatment group and control group, 50 cases in each group. Both groups were given antiplatelet drugs and antiarrhythmic drugs, On the basis of conventional treatment with atorvastatin 10 mg / d, the control group oral placebo, taking 1 year, followed 1.5 years. Results: The incidence of paroxysmal atrial fibrillation was reduced by> 50% in the treatment group than in the control group (P <0.05). The proportion of paroxysmal atrial fibrillation to persistent or permanent atrial fibrillation was changed. Incidence of left atrial enlargement, thromboembolism incidence were lower than the control group (P <0.05); follow-up period of patients with acute atrial fibrillation in the treatment group using amiodarone cardioversion dose and electrical cardioversion energy, the number was low In the control group (P <0.05). Conclusion: Atorvastatin can effectively prevent or reduce the onset of atrial fibrillation. During the treatment, nursing staff should give patients health education and psychological counseling, which can improve the prognosis and improve the quality of life.