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急性高原病(AMS)是急性暴露于高原(海拔>2500 m)或由高原进入更高海拔地区时,因高原低氧而在数小时至数天内出现的临床症候群。我国有着西藏、青海等大面积高海拔地区,随着高原旅游及务工人员的剧增,AMS严重威胁急进高原人群的健康、降低劳动能力。目前已知AMS发生率男性明显高于女性,青壮年高于老年和儿童,考虑AMS发生可能受体内性激素水平差异的影响。因此研究性激素与AMS的相关性对阐明AMS病理生理机制、预防和治疗AMS具有重要意义。
Acute altitude sickness (AMS) is a clinical syndrome that develops within hours to days due to altitude hypoxia when acute exposure to plateaus (altitudes> 2500 m) or altitude from altitude to altitude. China has large areas of high altitude such as Tibet and Qinghai. With the rapid growth of tourism and migrant workers on the plateau, AMS seriously threatens the health of the people who are entering the plateau rapidly and reduces their ability to work. It is known that the incidence of AMS is significantly higher in males than in females and young adults are higher than those in the elderly and children, considering the possible impact of AMS on the differences in sex hormones in the body. Therefore, the study of the correlation between sex hormones and AMS is of great significance for elucidating the pathophysiological mechanism of AMS and preventing and treating AMS.