环境和遗传因素均能影响多发性硬化症 (MS)的发生 ,且遗传因素也能影响该病的临床表现。受累同胞的病程一致性由遗传学决定。作者研究了家族因素对 MS临床表现及其严重程度的作用。家族因素系家庭成员所共有的遗传和环境因素。作者发现 MS同胞的病情严重程度具有一致性 ,这支持 Environmental and genetic factors can affect the occurrence of multiple sclerosis (MS), and genetic factors can also affect the clinical manifestations of the disease. The consistency of the affected sibs is genetically determined. The authors studied the role of familial factors in the clinical presentation and severity of MS. Family factors are the genetic and environmental factors common to family members. The authors found consistency in the severity of MS siblings and this support