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一般麻醉病人注射琥珀胆硷后血钾有轻度升高(0.25~0.8毫克当量/升),但大面积灼伤或损伤、神经肌疾患、破伤风病人静注琥珀胆硷后血钾显著升高,导致严重心律失常甚或心搏骤停。作者等研究事先注射潘侃朗宁(Pancuronium)可以预防琥珀胆硷引起的血钾升高。共有病人100例,年龄17~87岁(平均44.7),体格情况良好,无神经肌肉、心血管、酸硷及电解质紊乱,术前一小时用阿托品(0.4~0.6毫克),伴或不伴用吗啡(0.1毫克/公斤)或哌替啶(1毫克/公斤)。100例分四组,每组25例,全部病人用硫贲妥钠诱导(3~
General anesthesia patients after injection of succinylcholine increased slightly potassium (0.25 ~ 0.8 meq / l), but a large area of burn or injury, neuromuscular disease, tetanus intravenous injection of succinylcholine significantly increased serum potassium , Leading to serious arrhythmia or cardiac arrest. The authors study the Pancreonium injection of pre-injection can prevent the rise of potassium chloride caused by succinylcholine. A total of 100 patients, aged 17 to 87 years (mean 44.7), in good physical condition, no neuromuscular, cardiovascular, acid and electrolyte disorders, an hour before surgery with atropine (0.4 to 0.6 mg), with or without Morphine (0.1 mg / kg) or pethidine (1 mg / kg). 100 cases divided into four groups, 25 cases in each group, all patients induced by thiopental (3 ~