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目的 探讨儿科医院感染性肠炎 (NE)的发病情况、病原特点及相关因素 ,为该病的防治提供参考。方法 对近 10年来 12 8例NE患儿进行年龄、喂养方式、原发病情况、住院时间、抗生素应用等危险因素、病原体构成及药敏试验结果进行研究。结果 NE发病率为 1.33% ,占医院感染性疾病的 5 6 .89% ;NE原发病以恶性肿瘤、营养不良、新生儿硬肿症为主 ;病原体以白色念珠菌、变形杆菌属、枸橼酸杆菌属、铜绿假单胞菌为主 ;多数致病菌为耐药菌株 ,但对环丙沙星、妥布霉素、头孢曲松敏感株较多。结论 新生儿及婴儿是NE预防重点人群。加强支持治疗及病房消毒隔离制度 ,避免滥用抗生素可减少NE发生
Objective To investigate the incidence of pediatric hospital infectious enteritis (NE), pathogenic characteristics and related factors, provide a reference for the prevention and treatment of the disease. Methods A total of 128 cases of NE in the recent 10 years were studied in terms of age, feeding pattern, primary disease, length of hospital stay, antibiotic application, pathogen composition and susceptibility test results. Results The incidence rate of NE was 1.33%, accounting for 56.89% of the hospital infectious diseases. The main pathogenesis of NE was malignant tumor, malnutrition and neonatal scleredema. The pathogens were Candida albicans, Proteus, Citrobacter, Pseudomonas aeruginosa; most of the pathogenic bacteria were drug-resistant strains, but more sensitive to ciprofloxacin, tobramycin and ceftriaxone. Conclusion Neonates and infants are the major prevention population of NE. Strengthen supportive care and ward disinfection and isolation system, to avoid abuse of antibiotics can reduce the occurrence of NE