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本实验采用家兔肠粘连模型,观察了通腑活血药对肠粘连的预防作用及肠粘连程度与血中纤维蛋白原含量的关系。结果:①通腑活血药能预防或减轻肠粘连(P＜0.05);②通腑活血药能抑制术后血中纤维蛋白原含量的增加(手术前后比P＞0.05);③术后肠粘连程度与血中纤维蛋白原含量呈正相关。表明通腑活血药预防肠粘连的机理之一是抑制术后血中纤维蛋白原的生成。
In this experiment, rabbit intestinal adhesion model was used to observe the effect of Tongqiaohuoxue drug on intestinal adhesion and the relationship between intestinal adhesion and blood fibrinogen content. Results:1Tongqiao Huoxue Pills can prevent or reduce intestinal adhesion (P<0.05); 2 Tongqiao Huoxue Pills can inhibit the increase of postoperative blood fibrinogen content (P>0.05 before and after surgery); 3 Postoperative intestinal adhesion The degree is positively correlated with the fibrinogen content in the blood. One of the mechanisms of Tongluohuoxue in preventing intestinal adhesions is to inhibit the formation of fibrinogen in blood after surgery.