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目的分析研究极低出生体重儿(VLBWI)和超低出生体重儿(ELBWI)神经发育预后及影响因素。方法回顾性分析聊城市东昌府区妇幼保健院随机选取儿科收治并救活的VLBWI和ELBWI患儿80例,分为神经发育正常组及神经发育损害者各40例,分析可能的影响因素,以及神经发育预后情况。结果 80例患儿平均胎龄(30.0±2.2)周,胎龄28周15例,29~32周40例,>32周25例;出生体重平均为(1207.5±207.4)g,经多因素回归分析,脑损伤是VLBWI和ELBWI患儿神经发育损伤的独立危险因素。使用机械通气患儿的PDI得分低于未用者,两者具有统计学意义(P<0.05)。结论 VLBWI和ELBWI患儿神经发育受损发生率较高,尤其是接受机械通气治疗的患儿。
Objective To study the prognosis and influential factors of neurodevelopment in very low birth weight infants (VLBWI) and ultra low birth weight infants (ELBWI). Methods Retrospectively analyzed 80 children with VLBWI and ELBWI admitted to Dongchangfu District Maternal and Child Health Care Hospital of Liaocheng City randomly and divided into two groups of normal control group and 40 patients with neurodevelopmental impairment respectively. The possible influencing factors were analyzed. As well as the prognosis of neurodevelopment. Results The average gestational age was (30.0 ± 2.2) weeks in 80 cases, 15 cases in 28 weeks gestational age, 40 cases in 29 ~ 32 weeks and 25 cases> 32 weeks. The mean birth weight was (1207.5 ± 207.4) g, Analysis, brain injury is an independent risk factor for neurodevelopmental damage in children with VLBWI and ELBWI. Children with mechanical ventilation had lower PDI scores than those who did not (P <0.05). Conclusions Children with VLBWI and ELBWI have a higher incidence of neurodevelopmental impairment, especially in children undergoing mechanical ventilation.