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目的研究钬激光(Ho:YAG)加术后表阿霉素单次灌注治疗浅表性膀胱癌的临床疗效。方法自2001年1月至2002年5月,采用经尿道腔内钬激光(Ho:YAG)切除肿瘤加术后表阿霉素单次灌注治疗浅表性膀胱癌22例,其中单发肿瘤16例,多发肿瘤6例。病理分级移行细胞癌G1~G2、分期T1~T2。结果手术一次性成功,时间15~40min,术中无闭孔神经反射,无膀胱穿孔、大出血。术后灌注表阿霉素后无不良反应,1例6个月后复发,复发率4.5%,再次予钬激光处理治愈。结论钬激光加表阿霉素单次灌注治疗浅表性膀胱癌,复发率较低,是安全有效,方便易行的治疗方法。
Objective To study the clinical efficacy of holmium laser (Ho: YAG) combined with epirubicin single infusion in the treatment of superficial bladder cancer. Methods From January 2001 to May 2002, 22 cases of superficial bladder cancer were treated with transurethral holmium laser (Ho: YAG) and single epidural infusion of epirubicin. Among them, only tumor 16 For example, multiple tumors in 6 cases. Pathological grading transitional cell carcinoma G1 ~ G2, stage T1 ~ T2. The results of a one-time successful surgery, time 15 ~ 40min, intraoperative closed obturator nerve reflex, no bladder perforation, bleeding. Postoperative epirubicin perfusion without adverse reactions, 1 case of recurrence after 6 months, the recurrence rate of 4.5%, again treated with holmium laser cure. Conclusion Holmium laser plus epirubicin single infusion therapy for superficial bladder cancer, the recurrence rate is low, is safe and effective, convenient and feasible treatment.