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目的探讨新生儿败血症临床特征,以期早期诊断,早期治疗,降低病死率及后遗症发生率。方法对我院2008年5月至2011年5月3年来临床血培养阳性新生儿临床特征进行分析。结果新生儿败血症临床表现缺乏特异性;血培养仍是确诊的主要手段,WBC、PLT、CRP、微量血沉及PCT等非特异性检测指标中,PCT有相对较高的敏感性及特异性;高胆红素血症、化脓性脑膜炎、肺炎为最常见并发症。结论拟诊败血症患儿尽早行血培养,PCT检测,早期应用敏感抗生素控制感染,减少并发症,降低病死率。
Objective To explore the clinical features of neonatal sepsis in order to early diagnosis and early treatment, reduce mortality and sequelae incidence. Methods The clinical features of clinical blood culture positive neonates in our hospital from May 2008 to May 2011 were analyzed. Results The clinical manifestations of neonatal sepsis were lack of specificity. Blood culture was still the main means of diagnosis. PCT had relatively high sensitivity and specificity in WBC, PLT, CRP, micro-erythrocyte sedimentation rate and non-specific detection indexes such as PCT. Hypokalemia, purulent meningitis, pneumonia is the most common complication. Conclusions Children with suspected sepsis should undergo blood culture and PCT test as soon as possible, and use sensitive antibiotics to control infection early to reduce complications and reduce mortality.