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目的调查医院儿科患儿鲍氏不动杆菌感染情况、感染危险因素及耐药性,为儿科鲍氏不动杆菌感染的临床预防治疗提供参考依据。方法选取医院2012年12月-2015年12月儿科收治的患儿3 222例为研究对象,分离、培养并鉴定患儿的病原菌种类,对检出的鲍氏不动杆菌进行药敏试验,数据采用SPSS 19.0软件进行统计分析。结果 3 222例患儿样本中共培养出病原菌471株,以革兰阴性菌为主,共278株占59.02%;鲍氏不动杆菌是最主要的病原菌,占16.56%;机械通气、气管插管、抗菌药物使用时间和导尿管留置是患儿感染鲍氏不动杆菌的危险因素(P<0.05);鲍氏不动杆菌对氨曲南的耐药率最高,为97.44%。结论鲍氏不动杆菌是导致儿科感染的最主要病原菌,其对氨曲南的耐药率较高,对亚胺培南的耐药率较低,临床上应根据上述结果指导实施诊治。
Objective To investigate the prevalence of Acinetobacter baumannii infection, risk factors and drug resistance in children with pediatric pediatric patients in hospital and to provide reference for clinical prevention and treatment of Acinetobacter baumannii infection in children. Methods A total of 3 222 children admitted to our hospital from December 2012 to December 2015 were enrolled in this study. The pathogen types of children were isolated, cultured and identified. Susceptibility tests of the tested A. baumannii were performed. The data Using SPSS 19.0 software for statistical analysis. Results A total of 471 pathogenic bacteria were isolated from 3 222 children samples, mainly gram-negative bacteria, with a total of 278 strains accounting for 59.02%. Acinetobacter baumannii was the most important pathogen, accounting for 16.56%. Mechanical ventilation and endotracheal intubation , Antimicrobial time and urinary catheter indwelling were risk factors for infection with Acinetobacter baumannii (P <0.05). Acinetobacter baumannii had the highest resistance rate to aztreonam with 97.44%. Conclusion Acinetobacter baumannii is the most important pathogen causing pediatric infection. The drug resistance rate to aztreonam is high, and the resistance rate to imipenem is low. Clinical diagnosis and treatment should be based on the above results.