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五氯酚(PCP)和五氯酚钠(PCP—Na)广泛地用作木材防腐剂和除草剂。人体发生 PCP 工业中毒的一般临床症状是:食欲减退、体重减轻、发热(并可高达43℃、过度呼吸、头痛、眼和鼻粘膜充血、呼吸器官刺激症状、胸压迫感、虚弱以及神经痛。在皮肤接触之后,对局部皮肤有刺激作用并发生粉刺。Roberts 氏曾报告一例患者因皮肤连续接触 PCP1年左右发生致死性再生障碍性贫血。工业上至少已报导24例死亡病例,尸体解剖发现如下变化:脑水肿、心脏扩张、肾小管变性、肺充血水肿与肺泡内出血、肝轻度充血及肝小叶中央变性。
PCP and PCP-Na are widely used as wood preservatives and herbicides. The general clinical symptoms of PCP poisoning in the body are: loss of appetite, weight loss, fever (up to 43 ° C, over-breathing, headache, congestion of the eye and nasal mucosa, irritation of respiratory organs, chest compressions, weakness and neuralgia. After contact with the skin, it irritates the skin and acne occurs.Roberts has reported a case of persistent herpes simplex in a patient who has been exposed to PCP for 1 year due to skin contact. At least 24 deaths have been reported in the industry, and autopsy findings are as follows Changes: cerebral edema, cardiac dilatation, tubular degeneration, pulmonary congestion and edema and alveolar hemorrhage, mild hepatic hyperemia and hepatic lobule central degeneration.