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用琼脂稀释法测定Ｄｕ６８５９ａ对１２０６株临床分离菌的抗菌作用，并与其同类品种（司帕沙星、托舒沙星、诺氟沙星、氧氟沙星、左氟沙星、环丙沙星）比较。Ｄｕ６８５ｑａ对金葡球菌不产酶株、ＭＳＳＡ、ＭＲＳＡ、ＭＲＳＥ，溶血性链球菌和肺炎球菌的ＭＩＣ＿（９０）均为０．５ｍｇ／Ｌ；对肠球菌的ＭＩＣ＿（９０）为２ｍｇ／Ｌ，优于其同类品种。多数肠杆菌科细菌可为０．２５ｍｇ／Ｌ，铜绿假单胞菌可为０．５ｍｇ／Ｌ的本品所抑制，其抗菌活性与司帕沙星和托舒沙星相似。Ｄｕ６８５９ａ对各种厌氧菌亦具良好作用，多数菌株可为０．５ｍｇ／Ｌ的浓度抑制。因此认为本品具有良好的临床应用前景，值得进一步临床试验。
The antibacterial effect of Du6859a on 1206 clinical isolates was determined by agar dilution method. The antibacterial activity of Du6859a against its isolates (sparfloxacin, tosufloxacin, norfloxacin, ofloxacin, levofloxacin, ciprofloxacin ) Comparison. The MIC_ (90) of Du685qa against Staphylococcus aureus not producing enzymes, MSSA, MRSA, MRSE, hemolytic streptococcus and pneumococcus were both 0.5 mg / L and MIC 90 for Enterococcus was 2 mg / L, In its class. Most Enterobacteriaceae can be 0.25mg / L, Pseudomonas aeruginosa can be 0.5mg / L of the goods by the suppression of its antibacterial activity and sparfloxacin and tosufloxacin similar. Du6859a also has a good effect on various anaerobic bacteria, most of the strains can be 0.5mg / L concentration inhibition. So that this product has good clinical application prospects, it is worth further clinical trials.