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目的:探讨胸腺瘤合并重症肌无力(MG)的手术方式、围术期处理及疗效。方法:观察分析近12年48例胸腺瘤合并重症肌无力手术患者的手术方式和围手术期处理方法及术后随访结果。结果:完整切除肿瘤36例,肿瘤大部分切除10例,仅作活检者2例。无围手术期死亡。术后发生肌无力危象12例(25.0%)。术后MG症状缓解24例(50.0%)。结论:手术是治疗胸腺肿瘤合并MG的主要方法,手术效果及预后与手术切除范围、病理分期等因素有关,围手术期处理是否恰当直接影响手术的安全。
Objective: To investigate the surgical method, perioperative management and curative effect of thymoma combined with myasthenia gravis (MG). Methods: The surgical methods, perioperative management and postoperative follow-up of 48 patients with thymectomy and myasthenia gravis during recent 12 years were analyzed. Results: Totally 36 cases had complete resection of tumor, 10 cases had most resection of tumor, only 2 cases were biopsied. No perioperative deaths. Postoperative myasthenia gravis crisis in 12 cases (25.0%). Postoperative symptoms of MG remission in 24 cases (50.0%). Conclusion: Surgery is the main method for the treatment of thymus tumor combined with MG. The surgical effect and prognosis are related to the scope of surgical resection and pathological staging. Surgical treatment is directly related to the safety of the operation.