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研究表明,缺乏大脑低氧时,单独的颈动脉体(CB)低氧亦能诱发具有时间依赖性的进行性过度通气(即通气适应)。本文研究的目的在于确定CB没有低氧时,4小时以上的CNS低氧是否影响通气反应;除外,这种方式的低氧对中枢化学感受器刺激以及单独的CB刺激时的通气反应有无影响也是本文探讨的内容之一。实验在清醒山羊上进行,其CB血气可由体外循环机控制,而体系统(CNS)血气则独立地由吸入气水平决定。体系统动脉血PO_2降至40(?)(约含5.3KPa)时,CB处仍可维持正常氧供及正碳酸血状态;体系统动脉血PCO_2亦保持正碳酸血状态。结
Studies have shown that hypoxia alone in the absence of cerebral hypoxia also induces a time-dependent progressive hyperventilation (ie, ventilatory adaptation). The purpose of this study was to determine whether CNS hypoxia for more than 4 hours affected ventilatory response in the absence of hypoxia in CBs, with the exception of whether this mode of hypoxia had an effect on central chemosensory stimulation and CB stimulation alone This article explores one of the content. Experiments were performed on awake goats whose CB blood gas was controlled by an extracorporeal circulator and systemic gas (CNS) was independently determined by the level of inhaled gas. Systemic arterial blood PO_2 dropped to 40 (?) (About 5.3KPa), CB can still maintain normal oxygen supply and positive carbon dioxide state; systemic arterial blood PCO_2 also maintain positive carbonated blood. Knot