磺胺类药物临床应用頗广,为了便于患儿服用,多制成合剂、混悬剂或糖浆剂。目前,医院药房作快速分析,一般多采用亚硝酸鈉法,以碘化鉀淀粉指示液或对二甲氨基苯甲醛試紙作外指示剂的方法。虽然近年来,在测定方法上有一些改进,如采用室溫重氮化快速滴定法,但因采用外指示剂指示終点,尚有操作較麻煩、終点难判断、时間长、指示剂不能貯存或 Sulfa drugs widely used in clinical applications, in order to facilitate the children to take, and more made of mixture, suspension or syrup. At present, the hospital pharmacy for rapid analysis, the general use of sodium nitrite method to potassium iodide starch indicator solution or p-dimethylaminobenzaldehyde test paper for the external indicator method. Although in recent years, some improvements have been made in the determination methods, such as rapid diazotization at room temperature, but the use of external indicators to indicate the end point, there are more trouble to operate, the end is difficult to judge, a long time, the indicator can not be stored or