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目的 :探讨核仁形成区嗜银蛋白 (AgNOR)计数对宫颈良恶性病变鉴别诊断价值。方法 :采用AgNOR银染法对比 15例宫颈鳞癌与 2 2例慢性宫颈炎的AgNOR计数。结果 :宫颈鳞癌与宫颈良性病变的AgNOR计数差异有显著性 (P <0 0 1) ,宫颈不典型增生AgNOR计数也较宫颈良性增生上皮增高(P <0 0 5)。结论 :宫颈良恶性病变的AgNOR计数明显不同 ,此方法简便易行 ,可用于宫颈良恶性病变的鉴别。
Objective : To investigate the differential diagnostic value of AgNOR counts in benign and malignant lesions of the cervix. Methods : The AgNOR counts of 15 cases of cervical squamous cell carcinoma and 22 cases of chronic cervicitis were compared using AgNOR silver staining. Results: There was significant difference in AgNOR counts between cervical squamous cell carcinoma and cervical benign lesions (P <0 01). The AgNOR counts of cervical dysplasia were also higher than those of cervical benign hyperplasia epithelium (P <0 05). Conclusion : The AgNOR counts of benign and malignant lesions of the cervix are significantly different. This method is simple and easy to use and can be used for the identification of benign and malignant cervical lesions.