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目的探讨微波消融(microwave ablation,MWA)联合经皮无水乙醇注射(percutane-ous ethanol injection,PEI)能否扩大及优化肝组织的消融范围,为肝癌的临床治疗提供实验依据。方法应用新型注水式微波天线消融活体兔30只,分为单纯MWA及MWA+PEI(1.5ml)两组,观察相同的作用时间及功率组合下消融区域的大小及形态特征。结果在相同消融条件下,MWA+PEI的消融范围明显大于单纯MWA组(P<0.05)。结论 MWA+PEI可以明显扩大单针消融的范围,这将有利于提高肝癌的临床疗效。
Objective To investigate whether microwave ablation (MWA) combined with percutaneous-ous ethanol injection (PEI) can expand and optimize the range of ablation of liver tissue and provide experimental evidence for the clinical treatment of liver cancer. Methods Thirty newborn rabbits were ablated with a new type of water-injected microwave antenna and divided into simple MWA and MWA + PEI (1.5ml) groups. The size and morphological characteristics of the ablation zone under the same action time and power combination were observed. Results In the same ablation conditions, MWA + PEI ablation range was significantly greater than simple MWA group (P <0.05). Conclusion MWA + PEI can significantly expand the range of single-needle ablation, which will help improve the clinical efficacy of liver cancer.