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复习近年国内外公开发表的22篇白藜芦醇的抗肿瘤作用机制文献。白藜芦醇主要是通过抗氧化、抗自由基、抗异生素、抑制环氧化酶、抑制癌细胞增殖、诱导癌细胞分化和凋亡等多种途径达到抗肿瘤的作用。白藜芦醇通过多种机制参与了抑制恶性肿瘤生长的过程,了解其作用机制,将为白藜芦醇在恶性肿瘤的临床治疗应用方面提供实验基础,也为我国中草药的抗肿瘤效果的开发提供具体思路。
Review of 22 domestic and foreign published in recent years, the resveratrol antitumor mechanism of literature. Resveratrol mainly achieves antitumor effects through various pathways, such as antioxidation, anti-free radical, anti-xenobiotics, cyclooxygenase, inhibition of cancer cell proliferation, induction of cancer cell differentiation and apoptosis. Resveratrol participates in the process of inhibiting the growth of malignant tumor through a variety of mechanisms and understanding of its mechanism of action will provide the experimental basis for the clinical application of resveratrol in malignant tumors and also for the development of anti-tumor effect of Chinese herbal medicine Provide specific ideas.