目的　观察多瑞吉 (芬太尼贴剂 )治疗晚期癌痛患者的镇痛效果和不良反应。方法　 4 2例晚期癌痛患者 ,治疗前均为中、重度疼痛 ,使用多瑞吉镇痛治疗 ,每 2 4小时评定疗效一次 ,至少观察 15天。结果　全组完全缓解 5例 (11.9% ) ,明显缓解 31例 (73.8% ) ,总有效率为 85 .7%。不良反应主要为便秘、恶心呕吐、皮肤瘙痒及嗜睡等 ,发生率低。结论　多瑞吉治疗中、重度癌痛 ,镇痛效果好 ,不良反应小 ,值得临床进一步推广应用。 Objective To observe the analgesic effect and side effects of Duracell (fentanyl patch) in patients with advanced cancer pain. Methods Forty-two patients with advanced cancer pain were treated with moderate to severe pain before treatment. The patients were treated with Dorisi analgesia. The curative effect was evaluated every 24 hours for at least 15 days. Results In the whole group, 5 cases (11.9%) were relieved completely, 31 cases (73.8%) were relieved obviously, and the total effective rate was 85.7%. Adverse reactions mainly constipation, nausea and vomiting, skin itching and lethargy, the incidence is low. Conclusion Duorigi treatment, severe cancer pain, analgesic effect, adverse reactions, it is worth further clinical application.