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磺脲类药物受体 1(SUR1)在葡萄糖诱导胰岛素分泌过程中起重要作用 ,同时也是磺脲类药物结合点[1] 。SUR1基因是研究 2型糖尿病的重要候选基因之一[2 ] 。本研究的目的是探讨SUR1基因多态性与糖尿病、磺脲类药物疗效之间的关系。一、对象与方法1.研究对象 :2型糖尿病患者 15 5
Sulfonylurea receptor 1 (SUR1) plays an important role in glucose-induced insulin secretion and is also a sulfonylurea binding site [1]. SUR1 gene is one of the important candidate genes for studying type 2 diabetes [2]. The purpose of this study was to investigate the relationship between the SUR1 gene polymorphism and the efficacy of diabetes mellitus and sulfonylureas. First, the object and method 1. Research object: type 2 diabetes 15 5