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龋病是一种局部的感染性疾病,涉及到多种细菌的复杂作用。口腔细菌利用碳水化合物酵解所产生的有机酸使牙齿破坏,形成龋洞。龋洞形成之后,一些口腔细菌继续发挥作用,使龋洞进一步扩大,病变向深层进行。深龋微生物群体相当复杂。在深部牙本质龋损中,占统治地位的菌群是革兰氏阳性厌氧杆菌,高达44％。此外,还有革兰氏阳性兼性厌氧杆菌、球菌及少量革兰氏阴性厌氧菌。在龋病的后期阶段,牙本质小管中的球菌,首先到达牙髓。随着龋洞的扩大,任何口腔微生物成员均能到达牙髓。实际上,可以想象,在细菌到达牙髓之前。细菌
Caries is a localized infectious disease that involves the complex role of a variety of bacteria. Oral bacteria make use of organic acids produced by carbohydrate glycolysis to destroy the teeth and form cavities. After the formation of cavities, some oral bacteria continue to play a role, to further enlarge the cavities, lesions to the deep. Caries-rich micro-colonies are quite complex. In deep dentine caries lesions, the dominant flora is Gram-positive anaerobes, up to 44%. In addition, there are Gram-positive facultative anaerobes, cocci and a small amount of Gram-negative anaerobic bacteria. In the later stages of dental caries, the coccus in the dentinal tubules first reaches the pulp. As cavities expand, any oral microbial member can reach the pulp. In fact, it is conceivable that before the bacteria reach the pulp. bacterial