论文部分内容阅读
目的了解宝鸡地区2005年以后肾综合征出血热病监测情况及流行变化规律,为本地区出血热的防制提供科学依据。方法对宝鸡地区2005-2012年肾综合征出血热病人的急性期血清标本进行出血热IgM抗体实验室检测,分析阳性结果和流行病学调查资料。结果宝鸡地区2005-2012年肾综合征出血热IgM抗体阳性率为5.87/10万人口;2005-2008年阳性率呈缓慢下降趋势,2009-2011年缓慢增高,至2012年阳性率显著增高至21.88/10万人口;男性病人多于女性,性别差异有统计学意义(χ2=468.2,P=0.000<0.01);发病多集中于每年的10月至次年1月,符合姬鼠型出血热流行规律;发病人群以18~40岁青年和41~65岁中年人群居多,农民发病数最多,占83.31%。结论宝鸡地区2005年以后肾综合征出血热IgM抗体阳性率呈缓慢下降趋势,但近年又开始升高,尤其是2012年出现显著增高趋势。要继续加强本地区出血热防制措施,特别是开展灭鼠及对高发地区的青中年农民群体开展有针对性的出血热预防工作尤为重要。
Objective To understand the monitoring and epidemiological changes of hemorrhagic fever with renal syndrome in Baoji region from 2005 to provide a scientific basis for the prevention and control of hemorrhagic fever in this region. Methods Acute sera from patients with hemorrhagic fever with renal syndrome from 2005 to 2012 in Baoji region were tested in laboratory for IgM antibody against hemorrhagic fever with positive results and epidemiological investigation data. Results The positive rate of IgM antibody of hemorrhagic fever with renal syndrome in Baoji from 2005 to 2012 was 5.87 per 100 000 population. The positive rate showed a slowly decreasing trend from 2005 to 2008, and slowly increased from 2009 to 2011. The positive rate of IgM antibody increased to 21.88 / 100000 population; more male patients than women, the gender difference was statistically significant (χ2 = 468.2, P = 0.000 <0.01); incidence concentrated in every year from October to January next year, in line with Apodemus haemorrhagic fever The incidence of the disease was mostly between 18 ~ 40 years old and 41 ~ 65 years old middle age population. The incidence of peasants was the highest, accounting for 83.31%. Conclusions The positive rate of IgM antibody in hemorrhagic fever with renal syndrome in Baoji area shows a slowly decreasing trend after 2005, but it has begun to increase in recent years, especially in 2012. To continue to strengthen the prevention and control measures of haemorrhagic fever in this area, especially to carry out rodent control and carry out targeted hemorrhagic fever prevention work to young and middle-aged peasant groups in high incidence areas.