静吸复合全麻与全凭静脉麻醉对卵巢癌患者血清相关因子的影响

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目的 探讨静吸复合全麻和全凭静脉麻醉在卵巢癌患者中的使用.方法 选取2020年1月至2020年12月间上海市复旦大学附属华山医院收治50例卵巢癌患者,将患者根据不同麻醉方法分为对照组(静吸复合全麻)与观察组(全凭静脉麻醉)两组,每组25例.对比两组患者的CD3+、CD4+、一氧化氮(N0)和催乳素(PRL)影响.结果 观察组患者手术之后的CD3+和CD4+比对照组高,差异有统计学意义(P<0.05).两组患者在诱导前的血清NO含量比较,差异无统计学意义(P>0.05),两组切皮时和术中1h的血清NO含量都比诱导前高,且观察组的血清NO含量比对照组低,差异均有统计学意义(均P<0.05).两组患者在诱导前的血清PRL含量比较,差异无统计学意义(P>0.05).两组患者切皮时和术中1h的血清PRL含量都比诱导前高,且观察组的血清PRL含量比对照组低,差异均有统计学意义(均P<0.05).结论 全凭静脉麻醉在卵巢癌患者手术过程中应用能够提高患者麻醉效果,降低PRL浓度,缩短患者苏醒时间,值得临床推广使用.
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