历13年研究,对牛型分枝杆菌原始菌株进行200次以上培养,1921年卡介苗始于法国使用,自1950年后,它对全世界控制结核病发挥了极重要的作用。然而,近年来通过很多试验报告,其结果有了很大变化。最近在印度南部的一次令人沮丧的报道提出了应重新考虑接种卡介苗之价值。对卡介苗接种效果的争论:近50年来,通过群众性的卡介苗接种,并进行预期对比试验,发现其预防作用之幅度差异极为悬殊,竟由6%达80%,1950年,英国医学研究会对54329名14至15岁学生进行结核菌素试验,预防作用达78%。1978年英国胸科协会 Over 13 years of research, more than 200 cultures of the original strain of Mycobacterium bovis were carried out more than 200 times. Bacillus cereus started in France in 1921 and since 1950 has played an extremely important role in the control of tuberculosis throughout the world. However, in recent years, many test reports have been adopted and the results have changed dramatically. A recent depressing report in southern India raised the value of reconsideration of BCG vaccination. The controversy over the BCG vaccination effect: In the past 50 years, through mass BCG vaccination and the expected comparison test, it was found that the difference in the magnitude of its preventive effect was extremely disproportionate, ranging from 6% to 80%. In 1950, the British Medical Association 54,329 pupils aged 14 to 15 who took tuberculin test had a preventive effect of 78%. 1978 British Thoracic Society