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目的观察并探讨序贯机械通气治疗慢性阻塞性肺疾病(COPD)伴严重呼吸衰竭的效果。方法选取在2009年5月~2013年5月本院所收治的42例COPD伴严重呼吸衰竭病患,予以平喘以及抗感染等治疗,并用气管插管来实施有创机械通气,在出现肺感染控制窗以后,随机将42例病患分为对照组与观察组,两组病例各为21例,其中对照组继续采用有创机械通气来予以治疗,观察组将气管导管拔除,改用另外一种方式来予以治疗,即无创无压通气,对比两组病患呼吸机有关性肺炎发生率、总机械通气时间以及总住院时间。结果观察组与对照组不管是总机械通气时间、总住院时间,还是呼吸机有关性肺炎的发生率比较(P<0.05),差异有统计学意义。结论从本次研究的结果来看,对于COPD伴严重呼吸衰竭病采用序贯机械通气来予以治疗,相对于传统有创通气而言,其治疗效果更为显著,可有效缩短病患住院的时间以及总通气时间,使呼吸机有关性肺炎的发生率得到明显降低。
Objective To observe and discuss the effect of sequential mechanical ventilation on chronic obstructive pulmonary disease (COPD) with severe respiratory failure. Methods From May 2009 to May 2013, 42 COPD patients with severe respiratory failure admitted to our hospital were treated with antiasthmatic and anti-infective drugs. Tracheal intubation was used to implement invasive mechanical ventilation. In the presence of pulmonary Infection control window, the 42 patients were randomly divided into control group and observation group, 21 cases in each group, the control group continued to use invasive mechanical ventilation to be treated, the observation group will be removed from the tracheal tube, switch to another One way to treat this is noninvasive pressure-free ventilation comparing the incidence of ventilator-associated pneumonia, total mechanical ventilation, and total length of stay in both groups. Results The difference between the observation group and the control group was statistically significant (P <0.05) in terms of total mechanical ventilation time, total length of stay, or ventilator-associated pneumonia. Conclusions From the results of this study, sequential mechanical ventilation was used to treat COPD with severe respiratory failure. Compared with traditional invasive ventilation, the treatment effect is more significant, which can effectively shorten the hospitalization time As well as the total ventilation time, the incidence of ventilator-associated pneumonia was significantly reduced.