前列腺疾病是男性泌尿生殖系统的常见病,包括前列腺增生、前列腺癌等,多发生于中老年男性。前列腺是性激素依赖器官,其生长、分化等过程均需要性激素的调控。目前,环境中存在多种内分泌干扰物,可干扰体内正常内分泌激素的合成、释放、结合、代谢等,从而影响机体内环境稳态、生殖、发育及行为。研究表明,某些环境内分泌干扰物可影响前列腺疾病的发生和发展,本文对影响前列腺疾病的常见环境内分泌干扰物进行分类阐述,认为今后应加强相关人群资料的积累和人群流行病学的研究,探讨其发病机制,明确各类内分泌干扰物与前列腺疾病之间的关联。 Prostate disease is a common disease of the male genitourinary system, including benign prostatic hyperplasia, prostate cancer, etc., mostly in middle-aged men. Prostate is a sex hormone-dependent organ, its growth, differentiation and other processes require the regulation of sex hormones. At present, there are many kinds of endocrine disruptors in the environment, which can interfere with the synthesis, release, binding and metabolism of the normal endocrine hormones in the body, thereby affecting the homeostasis, reproduction, development and behavior of the body. Studies have shown that certain environmental endocrine disruptors can affect the occurrence and development of prostate diseases. This article describes the classification of common environmental endocrine disruptors that affect prostate diseases. In the future, it is believed that the accumulation of relevant population data and the population epidemiology should be strengthened. To explore its pathogenesis, a clear correlation between various types of endocrine disruptors and prostate disease.