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本文报告43例接受顺铂化疗肿瘤患者,使用国产恩丹西酮与胃复安随机自身对照止吐研究,结果表明在化疗的第1~3天恩丹西酮组的进食情况及恶心呕吐程度均好于胃复安组、在控制呕吐方面第1、2天恩丹西酮组亦明显的优于胃复安组,CR+PR分别为81.4%、58.1%和27.9%、32.6%。结果与进口柩复宁疗效相同,能有效地预防顺铂所致的胃肠道反应,尤其在控制顺铂所致的急性呕吐方面,疗效满意,可望取代柩复宁。
This article reports 43 cases of patients receiving cisplatin chemotherapy tumors, using homemade ondansetron and metoclopramide random self-control antiemetic study, the results showed that in the first 3 days of chemotherapy ondansetron group intake and nausea and vomiting Both groups were better than the metoclopramide group and on the 1st and 2nd days of control of vomiting. The ondansetron group was also significantly better than the metoclopramide group. CR+PR was 81.4%, 58.1%, and 27.9%, respectively. 32.6%. The results were the same as those of imported quinones, which can effectively prevent cisplatin-induced gastrointestinal reactions, especially in the control of acute vomiting caused by cisplatin. The efficacy is satisfactory, and it is expected to replace chlorpromazine.