论文部分内容阅读
目的探讨新疆和田维吾尔族长寿人群与非长寿人群的血脂水平及影响因素。方法选取1999—2012年在新疆和田地区生活的维吾尔族自然长寿老年人(年龄≥90岁)200例为长寿组;另选取同期在新疆和田地区生活且接受定期随访的维吾尔族非长寿人群(于59~73岁自然死亡)123例为非长寿组。收集两组一般资料并进行体格检查和实验室血脂指标检测,采用多因素Logistic逐步回归分析探讨长寿人群和非长寿人群患血脂异常的影响因素。结果两组性别比较,差异有统计学意义(P<0.05);非长寿组吸烟率高于长寿组,差异有统计学意义(P<0.05)。非长寿组身高、体质量高于长寿组,腰围、收缩压、高血压发生率低于长寿组,差异有统计学意义(P<0.05);两组BMI、舒张压比较,差异无统计学意义(P>0.05)。非长寿组总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、血脂异常发生率高于长寿组,高密度脂蛋白胆固醇(HDL-C)低于长寿组,差异有统计学意义(P<0.05);两组三酰甘油(TG)比较,差异无统计学意义(P>0.05)。多因素Logistic逐步回归分析结果显示,性别、腰围、收缩压、高血压是长寿人群发生血脂异常的影响因素(P<0.05),性别、BMI是非长寿人群发生血脂异常的影响因素(P<0.05)。结论长寿人群与非长寿人群均来自和田地区,但血脂水平、血脂异常发生率有明显差异;性别、腰围、收缩压、高血压是长寿人群发生血脂异常的影响因素,性别、BMI是非长寿人群发生血脂异常的影响因素。
Objective To investigate the level of blood lipid and its influencing factors in Uygur longevity and non-longevity populations in Wada, Xinjiang. Methods A total of 200 Uyghur longevity elderly (≥90 years old) living in the Hetian area of Xinjiang from 1999 to 2012 were selected as the longevity group. Another Uyghur non-longevity population who lived in the Hetian area in Xinjiang during the same period 59 to 73 years of natural death) 123 cases of non-longevity group. Two groups of general data were collected and tested for physical examination and laboratory lipid profile. Logistic regression analysis was used to explore the influencing factors of dyslipidemia in both longevity and non-longevity. Results There was significant difference in gender between the two groups (P <0.05). The smoking rate in non-longevity group was higher than that in longevity group (P <0.05). Non-longevity group height, body mass higher than longevity group, waist circumference, systolic blood pressure, hypertension incidence was lower than longevity group, the difference was statistically significant (P <0.05); BMI, diastolic blood pressure between the two groups, the difference was not statistically significant (P> 0.05). The incidence of total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and dyslipidemia in non-longevity group was higher than that in longevity group and HDL-C was lower than that in longevity group, with significant difference P <0.05). There was no significant difference in triglyceride (TG) between the two groups (P> 0.05). Multivariate logistic regression analysis showed that sex, waist circumference, systolic blood pressure and hypertension were the influencing factors of dyslipidemia (P <0.05), sex and BMI were the influencing factors of dyslipidemia in non-long-term population (P <0.05) . Conclusions Both longevity and non-longevity populations are from Hetian area, but there are significant differences in the level of blood lipid and dyslipidemia. Sex, waist circumference, systolic blood pressure and hypertension are the influencing factors of dyslipidemia in the longevity population. Gender and BMI are the non-longevity population The influencing factors of dyslipidemia.