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目的:分析国内三大中文数据库中医药治疗胰岛素抵抗文献用药规律。方法:使用病例信息采集表对纳入的194篇文献进行信息采集和录入,建立数据库,同时进行频数统计及聚类分析。结果:通过频数统计发现频数在40次以上中药13味。对此13味中药进行聚类分析,最终发现黄芪、黄连为治疗胰岛素抵抗主药,陈皮和半夏、葛根和山药以及生地和泽泻为基本药对,白术、陈皮、半夏、茯苓、苍术作为改善胰岛素抵抗的基本方。结论:以药测证发现脾虚、痰湿、瘀血、热毒,以及气阴两虚为胰岛素抵抗的基本病机。痰湿内阻尤为值得重视。
OBJECTIVE: To analyze the medication rules of TCM in the treatment of insulin resistance in three Chinese databases. Methods: Using the case information collection table, the 194 articles collected were collected and recorded, and the database was established. At the same time, frequency statistics and cluster analysis were performed. Results: Frequency statistics found that the frequency of more than 40 Chinese medicine 13 flavors. Thirteen traditional Chinese medicines were clustered and finally found that Astragalus and Coptis are the main drugs for the treatment of insulin resistance, dried tangerine peel and Pinellia tuber, Radix Puerariae and yam, as well as raw and Alisma orientalis, Atractylodes macrocephala, Tangerine peel, Pinellia ternata, Poria cocos As a basic way to improve insulin resistance. Conclusion: It is found that spleen deficiency, phlegm dampness, blood stasis, heat toxicity and Qi-Yin deficiency are the basic pathogenesis of insulin resistance. Phlegm resistance is particularly worthy of attention.