子宫肌瘤是盆腔最常见的良性肿瘤之一,是导致全子宫切除的主要原因之一。研究表明,孕激素在子宫肌瘤发病中起重要作用,米非司酮作为孕激素受体拮抗剂,可使肿瘤体积明显缩小,导致闭经,改善贫血[1]。应用孕激素拮抗剂米非司酮治疗子宫肌瘤以观察临床效果、全身状况及生活质量的影 Uterine fibroids are one of the most common benign tumors of the pelvis and one of the major causes of total hysterectomy. Studies have shown that progesterone play an important role in the pathogenesis of uterine fibroids, mifepristone as a progesterone receptor antagonist, can significantly reduce the size of the tumor, leading to amenorrhea and improve anemia [1]. Application of progestin antagonist mifepristone treatment of uterine fibroids to observe the clinical effects, general condition and quality of life shadow