论文部分内容阅读
长期以来,对柯兴氏病的病因和发病机理还有所争论,主要针对病因究竟是高级神经中枢异常引起促皮质激素(ACTH)分泌过多还是由于自主性垂体瘤所致。柯兴氏病经肾上腺切除术后的垂体功能状态也一直有争论。有认为生长激素(GH)及催乳素(PRL)的储备及周日节律消失、皮质醇分泌减少节律也消失,但也有人认为手术后下丘脑垂体功能仍属正常。本文作者对这一问题作进一步研究。柯兴氏病患者15例作为研究组,经双侧肾上腺切
For a long time, the etiology and pathogenesis of Cushing’s disease is still controversial, mainly for the cause of what is caused by abnormal high-level central nervous system corticotropin (ACTH) secretion or due to autonomic pituitary tumor. Cushing’s disease after adrenalectomy pituitary function status has also been controversial. Some believe that the growth hormone (GH) and prolactin (PRL) reserves and Sunday disappearance of rhythms, cortisol secretion to reduce the rhythm also disappeared, but some people think that hypothalamic pituitary function remains normal. The author of this article makes further research on this issue. Fifteen patients with Cushing’s disease were selected as study group and were treated by bilateral adrenalectomy