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Carrea等人认为,胃癌的发生分两个价段,第一个阶段时们很长,很可能超始于儿童期,以后逐渐发展,形成严重的萎缩性胃炎和肠化生;在第二阶段,上述胃粘膜病变继续发展,最终导致癌变。英国的统计数字表明,威尔士地区胃癌死亡率远高于南方各地,且体力劳动者高于脑力劳动者。本文探讨胃癌死亡率的地区差异和社会阶层的差别与维生素C摄入量和萎缩性胃炎的关系。慢性萎缩性胃炎和肠化生的诊断依据是,血清胃蛋白酶原(PGⅠ和PGⅡ)水平和维生素C水平,低水平的PGⅠ与胃炎的严重程度、恶性贫血、胃酸缺乏以及随后的胃癌危险性密切相关。鉴于萎缩性胃炎的发病率有随年龄急剧上升的趋势。故本文作者对巴斯城(胃癌死亡率低)和卡菲利城(胃癌死亡率高)两城515例65～74岁男性进行了调查,测定其血浆维生素C、PGⅠ和PGⅡ水平,探讨胃癌、
Carrea et al. believe that the incidence of gastric cancer is divided into two price segments. The first phase is very long. It is likely to begin in childhood and gradually develop later, resulting in severe atrophic gastritis and intestinal metaplasia; in the second phase The aforementioned gastric mucosal lesions continue to develop and eventually lead to cancerous changes. Statistics from the United Kingdom show that the death rate of gastric cancer in the Welsh region is much higher than that in the South, and that the number of manual workers is higher than that of mental workers. This article examines the regional differences in mortality from gastric cancer and the differences in social stratification with the relationship between vitamin C intake and atrophic gastritis. Chronic atrophic gastritis and intestinal metaplasia are diagnosed on the basis of serum pepsinogen (PGI and PGII) levels and vitamin C levels, low levels of PGI and gastritis severity, pernicious anemia, gastric acid deficiency, and subsequent risk of gastric cancer. Related. The incidence of atrophic gastritis has a tendency to increase rapidly with age. Therefore, the authors investigated 515 males aged 65 to 74 in the two cities of Bath City (low mortality rate in gastric cancer) and Kafelly City (high mortality rate in gastric cancer) and determined plasma levels of vitamins C, PGI, and PGII, and investigated gastric cancer. ,