论文部分内容阅读
目的探讨血清锌与急性脑梗死、冠心病和糖尿病的关系。方法选择2010年1月至2011年6月在我院神经内科、心血管内科、内分泌科住院患者以及健康体检中心正常人,分为4组:急性脑梗死组108例,冠心病组106例,糖尿病组105例,健康对照组101例。采用全自动生化分析仪测定血清锌浓度。结果急性脑梗死组、冠心病组、糖尿病组血清锌水平分别为(9.19±2.36)μmol/L、(9.23±2.67)μmol/L、(7.13±2.88)μmol/L,与健康对照组〔(13.55±2.99)μmol/L〕相比,差异均有统计学意义(P均<0.01)。糖尿病组与急性脑梗死组、冠心病组相比,差异均有统计学意义(P均<0.01)。结论急性脑梗死、冠心病和糖尿病患者的血清锌降低,糖尿病患者尤为明显,提示锌的缺乏可能是糖尿病及动脉粥样硬化的发病机制之一。
Objective To investigate the relationship between serum zinc and acute cerebral infarction, coronary heart disease and diabetes. Methods From January 2010 to June 2011 in our hospital neurology, cardiovascular medicine, endocrinology patients and healthy physical examination center normal, divided into four groups: 108 cases of acute cerebral infarction group, coronary heart disease group of 106 cases, 105 cases of diabetic group, 101 cases of healthy control group. Serum zinc concentration was measured by automatic biochemical analyzer. Results Serum zinc levels were (9.19 ± 2.36) μmol / L and (9.23 ± 2.67) μmol / L and (7.13 ± 2.88) μmol / L respectively in acute cerebral infarction group, coronary heart disease group and diabetic group, 13.55 ± 2.99) μmol / L], the differences were statistically significant (all P <0.01). There was significant difference between diabetic group and acute cerebral infarction group and coronary heart disease group (all P <0.01). Conclusions Serum zinc is decreased in patients with acute cerebral infarction, coronary heart disease and diabetes mellitus, especially in diabetic patients, suggesting that zinc deficiency may be one of the pathogenesis of diabetes and atherosclerosis.