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目的:分析采用米非司酮联合甲氨蝶呤(MTX)治疗和单药甲氨蝶呤保守治疗未破裂异位妊娠的治疗效果。方法:选择2004年1月～2007年12月到我院就诊,诊断为未破裂型异位妊娠应用药物保守治疗的患者156例。随机分为治疗组和对照组。治疗组78人采用米非司酮联和甲氨碟呤治疗,对照组78人采用甲氨碟呤治疗,结果:治疗组成功率高于对照组,疗程更短,重复使用MTX次数更少,药物毒副反映及输卵管通畅率二者相比差异无显著性(P<0.05)。结论:米非司酮联合MTX保守治疗合适的异位妊娠成功率高,提高了将来生育率,疗程缩短,安全,可靠,简便,值行临床推广。
OBJECTIVE: To analyze the efficacy of conservative treatment of unruptured ectopic pregnancy with mifepristone plus methotrexate (MTX) and monotherapy with methotrexate. Methods: A total of 156 patients with conservative treatment of unruptured ectopic pregnancy who were admitted to our hospital from January 2004 to December 2007 were selected. Randomly divided into treatment group and control group. 78 patients in the treatment group were treated with mifepristone and methotrexate, and 78 in the control group were treated with methotrexate. The results showed that the treatment group had higher success rate than the control group, with a shorter course of treatment and less repeated MTX. Drugs There was no significant difference between the two groups in toxicity and tubal patency (P <0.05). Conclusion: Mifepristone combined with MTX conservative treatment of ectopic pregnancy with high success rate, to improve the future fertility rate, shorten the course of treatment, safe, reliable, simple, the value of clinical promotion.