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目的分析研究中药的不良反应,为其临床合理用药提供依据。方法选取医院2012年3月-2016年1月收治的使用中药治疗过程中发生不良反应的患者121例为研究对象,回顾分析涉及患者的基本资料及用药情况,统计不良反应涉及的主要系统、相关表现,并据此提出临床合理用药的措施。结果年龄<18岁或>60岁,以静脉注射方式给药患者中药不良反应发生率显著高于其他年龄段和给药途径的患者,而皮肤黏膜和消化系统的不良反应发生率最高。结论中药不良反应的发生与多方面因素有关,分析造成不良反应的主要原因,并给予积极防控,对于促进临床合理用药具有积极意义。
Objective To analyze and study the adverse reactions of traditional Chinese medicine (TCM) and provide evidence for its clinical rational use. Methods A total of 121 patients with adverse reactions during the course of TCM treatment from March 2012 to January 2016 in our hospital were selected as the research objects. The patients’ basic information and medication were retrospectively analyzed. The main systems involved in adverse reactions were statistically analyzed. Performance, and accordingly put forward the clinical rational use of measures. Results Age <18 years old or> 60 years old, the incidence of adverse reactions of traditional Chinese medicine in patients receiving intravenous injection was significantly higher than that in other age groups and administration routes, while the adverse reactions of skin mucosa and digestive system were the highest. Conclusion The occurrence of adverse reactions of traditional Chinese medicine is related to many factors. It is of great significance to analyze the main causes of adverse reactions and to provide active prevention and control to promote clinical rational use of drugs.