近年来克山病的流行特点起了明显的变化:就全国范围来看,在发病率大大下降的同时,病区面积却明显扩大;在发病人群方面,东北病区,早期以妇女发病为多见,而近年来儿童发病跃居主要地位,南方病区发病人群几全属儿童。这些变化,目前迄无恰当解释。由于硒缺乏已被证实是克山病发病的基本因素,本文引用了五十年代大量的克山病发病和死亡率调查资料,论证病区居民对低硒环境可能存在代谢适应能力。据此,对当前克山病流行特点的变化进行了较为合理的解释,并对未来克山病流行趋势进行了预测。 In recent years, the prevalence of Keshan disease has played a significant change: From a national point of view, the incidence rate dropped significantly at the same time, the ward area was significantly expanded; in the incidence of people, the northeastern area, the early onset of women as much See, and in recent years the incidence of children leapt to the main status of the southern ward almost all the incidence of children belonging to children. As of now, these changes have not been properly interpreted. Because selenium deficiency has been proved to be the basic factor in the pathogenesis of Keshan disease, this article refers to a large number of Keshan disease incidence and mortality survey data in the 1950s to demonstrate that residents in the ward may have metabolic adaptability to low selenium environments. Accordingly, the current Keshan disease epidemic characteristics of the changes made a more reasonable explanation, and future Keshan disease epidemic trends were predicted.