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目的探讨欣普贝生联合乳头刺激用于孕晚期羊水减少患者分娩诱导的效果及安全性。方法 55例孕晚期羊水减少患者,按抽签法分为研究组(23例)和对照组(32例)。研究组给予阴道后穹窿置入欣普贝生并联合乳头刺激,对照组仅给予乳头刺激。比较两组干预后宫颈Bishop评分和分娩结局。结果研究组促宫颈成熟效果显著,72 h内有效率达91.30%(21/23),缩宫素使用率8.70%(2/23),阴道分娩率73.91%(17/23),剖宫产率26.09%(6/23),对照组促宫颈成熟效果72 h内有效率达46.88%(15/32),缩宫素使用率31.25%(10/32),阴道分娩率40.63%(13/32),剖宫产率59.38%(19/32),两组比较差异均有统计学意义(P<0.05);两组羊水粪染、新生儿窒息、产褥感染发生情况比较差异均无统计学意义(P>0.05)。结论欣普贝生联合乳头刺激用于孕晚期羊水减少患者的分娩诱导安全有效,可提高自然分娩率,降低缩宫素使用率及剖宫产率。
Objective To explore the effect and safety of Enbu Beisheng combined with nipple stimulation in labor induction induced by amniotic fluid reduction in the third trimester of pregnancy. Methods 55 cases of amniotic fluid reduction in third trimester were divided into study group (23 cases) and control group (32 cases) according to the method of lottery. The study group was given Xinpisibeheng vaginal fornix combined with nipple stimulation, the control group was given nipple stimulation. Cervical Bishop score and delivery outcome were compared between the two groups. Results In the study group, the effect of promoting cervical ripening was remarkable. The effective rate was 91.30% (21/23) within 72 h, oxytocin utilization rate was 8.70% (2/23), vaginal delivery rate was 73.91% (17/23) (26.09%, 6/23). The effective rate of cervical ripening in control group was 46.88% (15/32) in 72 h, the rate of oxytocin was 31.25% (10/32) and vaginal delivery rate was 40.63% (13 / 32). The rate of cesarean section was 59.38% (19/32), there were significant differences between the two groups (P <0.05). There was no statistical difference in the incidence of meconium amniotic fluid, neonatal asphyxia and puerperal infection between the two groups Significance (P> 0.05). Conclusions The combination of Xinpibisheng and nipple stimulation in the delivery of amniotic fluid during the third trimester of pregnancy is safe and effective. It can increase the rate of natural childbirth and reduce the rate of oxytocin and the rate of cesarean section.