氟骨症的临床特征以骨和骨关节症状为主。初期仅表现为关节疼痛,并且疼痛部位不游走、不发热,不受气候变化的影响,关节活动受限;严重时则会出现肢体变形,甚至瘫痪。当骨质增生、变形压迫神经时,还可出现感觉迟钝或过敏,肢体麻木,肌张力增高或减弱,肌无力,头晕,腹胀,便秘,大小便失禁等。实验室检查可见尿氟、发氟、血氟和碱性磷酸酶 The clinical features of skeletal and bone and joint symptoms of bone-based. The initial performance of only joint pain, and the pain does not walk away from the site, not fever, freedom from climate change, joint activity is limited; severe cases there will be limb deformity, or even paralyzed. When the bone hyperplasia, deformation oppression nerve, but also may be feeling insensitive or allergic, limb numbness, increased or decreased muscle tone, muscle weakness, dizziness, bloating, constipation, incontinence and so on. Laboratory tests showed urine fluorine, hair fluoride, blood fluoride and alkaline phosphatase