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地方性克汀病是一种发生在地方性甲状腺肿流行区,以智力障碍为主要临床表现,并伴有其它神经学缺陷的综合征。有关该病的临床资料国内外报告较多,但病理形态学研究,尤其超微结构的研究。文献记载甚少。我们曾对一例神经型克汀病死亡患者的脑及甲状腺等内分泌器官做了光镜和电镜的形态学观察。
Local Creutzfeldt-Jakob disease is a syndrome that occurs in endemic goiter endemic areas and is characterized by mental retardation as a primary clinical manifestation accompanied by other neurological deficits. The clinical data on the disease more reports at home and abroad, but the pathological morphology, especially ultrastructure. Little documented. We have done a morphological observation by light and electron microscopy on the brain and thyroid and other endocrine organs in a patient who died of neurological cretinism.