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系统性红斑狼疮(SLE)是自身免疫病的典型代表。病人体内存在的高滴度抗DNA抗体与SLE病原和病理有着密切的联系。因此,人们对此作了大量的研究工作。1984年,Isenberg等人用5例活动期SLE病人的淋巴细胞建立
Systemic lupus erythematosus (SLE) is a typical manifestation of autoimmune disease. High titers of anti-DNA antibodies present in the patient’s body are closely linked to the pathogens and pathologies of SLE. Therefore, people made a lot of research work on this. In 1984, Isenberg et al. Established lymphocytes from 5 patients with active SLE