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据Guan M 2012年2月5日(Nat Med,2012 Feb 5.doi:10.0138/nm.2665)报道,美国加州大学戴维斯分校一个研究小组开发出一种利用分子增强骨生长的新技术:当该分子被注射进血液,它指导身体的干细胞运行到骨表面。一旦这种分子指导干细胞到达骨表面时,这些干细胞分化为成骨细胞而且合成促进骨生长的蛋白。该研究利用骨质疏松(osteoporosis)模型小鼠证实人们可以利用一种独特的方法增加骨质密度和阻止与衰老和雌激素缺乏相关联的骨质流失。
According to a report by Guan M on February 5, 2012 (Nat Med, 2012 Feb 5. doi: 10.0138 / nm.2665), a team from the University of California, Davis, USA, developed a new technique that exploits molecular growth enhancements: When the molecule is injected into the blood, it directs the body’s stem cells to run onto the bone surface. Once such molecules guide the stem cells to reach the bone surface, these stem cells differentiate into osteoblasts and synthesize proteins that promote bone growth. The study used osteoporosis model mice to demonstrate that one could use a unique approach to increase bone density and prevent bone loss associated with aging and estrogen deficiency.